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    Secondary Metabolite Isolation From Indonesian Folious Lichen: Phyloporon Aciculare (ACH.)

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    FISIP_SECONDARY METABOLITE ISOLATION FROM INDONESIAN FOLIOUS LICHEN (1).pdf (1.339Mb)
    Date
    2022-12-03
    Author
    PUTRI, C. P. Z. S.
    LAKSONO, T. A.
    PRATOKO, D. K.
    TRIATMOKO, B.
    PRATAMA, A. N. W.
    SISWOYO, T. A.
    UNTAR, L. F.
    Wongso, H.
    HENDRA, R.
    KELLER, P. A.
    NUGRAHA, A. S.
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    Abstract
    Lichen has been investigated for discovering new antibacterial agents. Although Indonesia is considered one of the megadiverse countries and a home to a diverse array of lichen species, research on lichens for medicinal properties remains scarce. In this study, an intensive semi-preparative High-Performance Liquid Chromatography successfully isolated a major compound from Phyloporon aciculare, with its molecular structure proposed as methyl 2,4- dihydroxy-3,6-dimethylbenzoate by Nuclear Magnetic Resonance spectral and was confirmed by Mass Spectrometry data analysis. The crude extract of the lichen possessed a selective antibacterial activity in which significantly inhibited Kocuria rhizophila by 96.9% at a 100 µg/mL concentration. In addition, previous reports on methyl 2,4-dihydroxy3,6-dimethylbenzoate from other species indicated the compound to have antibacterial, anti-inflammatory, and anticancer activities.
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    https://repository.unej.ac.id/xmlui/handle/123456789/114115
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    • LSP-Jurnal Ilmiah Dosen [7410]

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    UPA-TIK Copyright © 2024  Library University of Jember
    Contact Us | Send Feedback

    Indonesia DSpace Group :

    University of Jember Repository
    IPB University Scientific Repository
    UIN Syarif Hidayatullah Institutional Repository