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    Antimicrobial Activities of Nano-Emulsion of Virgin Coconut Oil

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    FAPERTA_JURNAL_Antimicrobial Activities of Nano-Emulsion of Virgin Coconut Oil.pdf (692.1Kb)
    Date
    2023
    Author
    WIDIANINGRUM, Desy Cahya
    KHASANAH, Himmatul
    PURNAMASARI, Listya
    KRISMAPUTRI, Melinda Erdya
    HWANG, Seong Gu
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    Abstract
    This study aimed to determine the nano-emulsion of virgin coconut oil (n-VCO) formula that can produce the best size and zone inhibition of antimicrobial activity. The VCO was formulated with the different percentages of Tween 80 (P1: 24%, P2: 25%, P3: 26%) and sorbitol (P1: 36%, P2: 35%, P3: 34%). The particle size of the n-VCO emulsion was observed under transmission electron microscopy (TEM). The antimicrobial activity test of the n-VCO was determined by a challenge test using Salmonella Typhi (S. Typhi), Staphylococcus aureus (S. aureus), and Escherichia coli (E. coli) bacteria. The data were analysed by a one-way ANOVA (P < 0.05). The significant data were furthermore tested by Duncan’s multiple ranges (SPSS v26.0). This study showed that the P3 formulation (26% Tween 80 and 34% sorbitol) produced the best n-VCO among all the treatments showing a particle size of 5–100 nm. Formulas P1 and P2 produced particle sizes of about 500–1 000 nm. The antimicrobial test showed that the P3 formula had a strong inhibitory effect on S. Typhi (7.442 ± 0.52 mm), S. aureus (8.380 ± 0.49 mm), and E. coli (6.490 ± 0.82 mm). This study concluded that the formula of the detergent strongly influences the particle size of the n-VCO. The n-VCO has enormous potential to be used as an alternative antimicrobial.
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    https://repository.unej.ac.id/xmlui/handle/123456789/112687
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    • LSP-Jurnal Ilmiah Dosen [7368]

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    UPA-TIK Copyright © 2024  Library University of Jember
    Contact Us | Send Feedback

    Indonesia DSpace Group :

    University of Jember Repository
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