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dc.contributor.authorSawitri, Widhi Dyah
dc.contributor.authorSlameto, Slameto
dc.contributor.authorSugiharto, Bambang
dc.contributor.authorKyung-Min Kim
dc.date.accessioned2020-01-20T08:24:43Z
dc.date.available2020-01-20T08:24:43Z
dc.date.issued2012-03-18
dc.identifier.urihttp://repository.unej.ac.id/handle/123456789/97049
dc.description.abstractStudies into the cell death program termed apoptosis have resulted in new information regarding how cells control and execute their own demise, including insights into the mechanism by which death-preventing factors can inhibit Bax-induced caspase activation. We investigated high temperature stress-induced cell death in Brassica rapa. Using a yeast functional screening from a Brassica rapa cDNA library, the BH5-127 EST clone encoding an apoptotic suppressor peptide was identified. However, a phylogenic tree showed that BH5-127 clusters within a clade containing SUMO-1 (Small Ubiquitin-like Modifier1). BH5-127 was confirmed similar to have function to SUMO-1 as Fas suppression. Expression of BH5-127 showed that substantial suppression of cell death survived on SD-galactose-Leu - - medium. The results suggest that BrSE (Brassica rapa Sentrin EST, BH5-127) is one of the important regulatory proteins in programming cell death, especially in the seedling stage of Chinese cabbage.en_US
dc.language.isoenen_US
dc.publisherJ. Microbiol. Biotechnol. (2012), 22(5), 600–606en_US
dc.subjectApoptosisen_US
dc.subjectBrassica rapaen_US
dc.subjectsentrinen_US
dc.subjectSUMO-1en_US
dc.subjectyeast functional screeningen_US
dc.titleIdentification of Chinese Cabbage Sentrin as a Suppressor of Bax-Induced Cell Death in Yeasten_US
dc.typeArticleen_US
dc.identifier.kodeprodiKODEPRODI2520101#Magister Bioteknologi
dc.identifier.nidnNIDN0022105504


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