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    The correlation of consuming thymoquinone extract of nigella sativa to tooth socket re-epithelization on diabetic induced rats

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    Date
    2018-11-01
    Author
    Syafriadi, Mei
    Yusuf, Putri R.
    Pratama, Sabrina M.
    Ummah, Dina Z.
    Amalia, Khoirul
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    Abstract
    Objective: The purpose of this research is to determine the effect of Tq to re-epithelialization at the margin of tooth socket post extraction in diabetic rats. Material and Methods: Used 27 rats were induced diabetic with streptozotocin (STZ) dose of 50 mg/kg body weight of rats which divided into 3 groups that has been stained with hematoxillin-eosin and cytokeratin 19. They are P1 treated with thymoquinone (Tq), P2 treated with metformin, and K without treatment. Each group consist of 9 rats were divided into 3 subgroups based on day of observation. They are 3rd, 7th and 10th day post-extraction. Re-epithelialization was observed at the margin of the tooth socket that has been stained with hematoxillin-eosin and cytokeratin 19 Results: showed there was an improvement of re epithelialization percentage in the Tq treatment group compared with P2 and K groups. Conclusion: Thymoquinone extract may decrease blood glucose level and increasing re-epithelialization in margin of the tooth socket after extraction in diabetic rats.
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    http://repository.unej.ac.id/handle/123456789/87580
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    • LSP-Jurnal Ilmiah Dosen [7410]

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    Indonesia DSpace Group :

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