dc.contributor.author | Mayasari Kurnia N. D. | |
dc.date.accessioned | 2013-12-12T09:49:44Z | |
dc.date.available | 2013-12-12T09:49:44Z | |
dc.date.issued | 2013-12-12 | |
dc.identifier.nim | NIM092210101055 | |
dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/8663 | |
dc.description.abstract | ABSTRAK
1-(4-nitrobenzoiloxymethyl)-5-fluorouracil were synthesized from a lead
compound 5-fluorouracil (5FU), an anticancer commonly used for treating breast
cancer. The compound were synthesized by two steps, the substitution of
hydroxymethyl to N1 position of 5-FU followed by esterification by 4-
nytrobenzoilcloride. The product were purified by coloumn chromatography and
identified by 1HNMR and FTIR-KBr. The purity was characterized by TLCDensitometry
and its melting point range. Finally, the compound was synthesized
successfully. | en_US |
dc.language.iso | other | en_US |
dc.relation.ispartofseries | 092210101055; | |
dc.subject | 1-4-nitrobenzoyloxymethyl-5-fluorouracil 5-fluorouracil anticancer benzoylation | en_US |
dc.title | SINTESIS 1-(4-NITROBENZOILOKSIMETIL)-5- FLUOROURASIL SEBAGAI PENGEMBANGAN OBAT KANKER | en_US |
dc.type | Other | en_US |