Metabolic Isotope Labeling of Polysaccharides with Isotopic Glucose for Quantitative Glycomics in Cell Culture
Date
2017-11-27Author
Hyun-Kyeong Seo
Fanata, Wahyu Indra Duwi
Sang-Jin Kim
Seongha Park
Yong-Ill Lee
Kyun Oh Lee
Jae-Min Lim
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Show full item recordAbstract
The attachment of sugars to the side chains of proteins via
glycosylation is a common post-translational modification
that plays significant roles in a wide range of biological
processes in living organism. The majority of extracellular
matrix and the membranous proteins are highly glycosylated
by N-linked glycans as well as other types of
glycans. A change in glycome profiles and the expression
levels of proteins responsible for glycan complexity has
been reported in a variety of disease states and during the
course of developmental processes.
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