Daya Hambat Ekstrak Daun Kamboja Putih (Plumeria acuminata) TerhadapStreptococcus mutans

Abstract

Background: Most of carries were caused by Streptococcus mutans. White frangipani leaves ethanol extract were alleged to control the growth of Streptococcus mutans. This extract contains antibacterial compound such us flavonoid, saponin, tannin, and alkaloid. Purpose: This study was to find out antibacterial activity of white frangipani leaves ethanol extract against the growth of Streptocossus mutans. Method: This study was well diffusion method with 6 treatment groups. Each petridish was filled BHI-A and inoculated by S. mutans followed by making 6 wells using the borer (diameter 5 mm). Extracts 50%, 25%, 12.5%, 6.25%, positive and negative control were added into the wells at concentration of 20 µL for each material. Then the incubation was carried out at a temperature of 37oC for 24 hours then inhibitory zones were measured. Results: this study showed that there were inhibitory zones in positive control, extract 50%, and 25% treatment groups and weren’t nhibitory zones in negative control, extract 12,5%, and 6,25%. Conclusion: White frangipani leaves ethanol extract has antibacterial activity against the growth of Streptococcus mutans with minimum nhibitory concentration of 25%.