dc.description.abstract | Background. Dental pulp inflammation was progress of the caries process. The
most common of pulp inflammation was caused by penetration of Streptococcus mutans.
Streptococcus mutans will colonize and cause injury to the pulp tissue by infiltrating
inflammatory cells. Currently, very less experimental studies talked about pulp
inflammation. Objective. This research aimed to analyze the increase number of
inflammatory cells PMN, macrophages and lymphocytes in mice exposed Streptococcus
mutans in the pulp. Method. This study used experimental laboratory, the sample divided
into three groups, control group (left molar RB rats were intact without treatment), P1 group
(left molar RB rats were prepared to pulp perforation), and P2 group (molar RB rats were
prepared to pulp perforation and induced Streptococcus mutans in the pulp chamber).
Results. The highest average number of PMN inflammatory cells, lymphocytes and
macrophages was in P2 group. PMN cells and lymphocytes found in both treatment
groups (P1 and P2), whereas macrophage cells found only in P2 group. Inflammatory cells
were not found in the control group. Conclusion. it could be concluded that
Streptococcus mutans exposure could increase the number of inflammatory cells such as
PMN, lymphocytes and macrophages. | en_US |