| dc.description.abstract | Catfish is a kind of fish that is often stricken with disease especia to overcome this problem catfish farmers do treatment
and prevention by injecting oxytetracycline in to Intra-abdominal cavity area.
Oxytetracycline is a derivative antibiotic of tetracycline that is produced by
Streptromyces rimosus. Oxytetracycline is yellow, bitter, and has high solubility in
acid and solubility low in water. Oxytetracycline is a drug with broad spectrum
that can be easily absorbed in our body and it makes metabolism process run
easily. The use of oxytetracycline in the cultivation of fresh water fish is not
allowed because the accumulation of antibiotic residues in fish in a long period
will cause various diseases such as tumor, cancer, and the other generative
disease. In this study, we will develop an a method of analysis Oxytetracycline
residue level in catfish by KCKT Uv-Vis with a detector that has high sensitivity,
good resolution, and can analyze low quantity of sample such as in determining
residue level. To guarantee the validity of the method, it was done a validity test
toward the developed method. The result obtained that the method was valid and
it has linearity of calibration R = 0,9972, precision with KV precision between =
3,54 % for dosage 40 mg and 5,73% for dosage 120 mg, and accurate with
average score % recovery = 95,938 % for dosage 40 mg and 103,367 % for
dosage 120 mg. Residue level that was obtained was 0,412 % in the catfish that
was given dosage Oxytetracycline 40 mg and 0,730% to the catfish that was given
dosage 120 mg. | en_US |
