| dc.description.abstract | Healthcare-Associated Infections (HAIs) is a bacterial infections in Indonesia caused by
Staphylococcus aureus. According to the World Health Organization (WHO), the prevalence of HAIs in
developing countries varies between 5.7% and 19.1% with a combined prevalence of 10.1%. The prevalence of HAIs in Indonesia is 7.1%. Infections caused by bacteria are a life-threatening disease, which
needs to be treated immediately by administering antibacterial agents. One of the natural products with
potential as new antibacterial agents, such as soil fungi. This research aims to discover the Antibacterial
activity of fungi on estuary land at Pasir Putih village, Situbondo, East Java. This research was initiated
by growing the soil on the PDA media to isolate six fungi which were labeled as IS-B1-A1, IS-B1-A2,
IS-B1-T1, IS-B1-T2, IS-B1-B1, and IS-B1-B2. All the isolated fungi were separately fermented for 14 d
and extracted using ethyl acetate before the microdilution test. The result of antibacterial testing showed
all extracts from isolated fungi with code IS-B1-A1, IS-B1-A2, IS-B1-T1, IS-B1-T2, IS-B1-B1, and
IS-B1-B2 possessed antibacterial activity against Staphylococcus aureus with percentage inhibition of
51.1±2.6%; 84.6±3.1%; 72.7±7.9%; 82.9±7.6%; 65.6±0.8%; 88.2±2.8% at a concentration of 100 μg/mL. | en_US |
