Show simple item record

dc.contributor.authorGIANOSA, Giovani
dc.contributor.authorSURYONO, Suryono
dc.contributor.authorSANTOSO, Ali
dc.date.accessioned2022-06-02T06:50:51Z
dc.date.available2022-06-02T06:50:51Z
dc.date.issued2022-04-26
dc.identifier.govdocKODEPRODI2010101#Pendidikan Dokter
dc.identifier.govdocNIDN0004095909
dc.identifier.urihttp://repository.unej.ac.id/xmlui/handle/123456789/106967
dc.description.abstractDiabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia that occurs due to abnormalities in insulin secretion. Chronic hyperglycemia in diabetes causes dysfunction and failure of various organs of the body such as the kidneys, eyes, nerves, heart and blood vessels. The purpose of this study was to analyze how the effect of the treatment given by Moringa leaves on diabetes mellitus conditions, especially on glomerular histopathological damage. In this study, to make diabetic mice using the induction of streptozotocin after which Moringa leaves were given as a form of treatment. The dosage of Moringa leaf extract was divided into 5 groups, namely 62.5mg / kg, 125mg / kg, 250mg / kg, 500mg / kg, and 1000mg / kg doses. The histopathological image obtained will be assessed using scoring, and for data analysis using the Kruskal-Wallis test and followed by the post hoc test using the Mann-Whitney test. The results of this study indicate that there is an effect of giving Moringa leaf extract on glomerular histopathological damage. The results of the Kruskal-Wallis data analysis test showed significant results, namely p = 0.001, after the data obtained were significant data, then it was continued with the post hoc test using the MannWhitney test with significant results when compared with negative controls ranging from the 125mg / kg dose group 1000mg / kg.en_US
dc.language.isoenen_US
dc.publisherNurseLine Journalen_US
dc.subjectDiabetes,en_US
dc.subjectMoringaen_US
dc.subjectMoringa Oleifera Lamken_US
dc.subjectRenoprotectiveen_US
dc.subjectStreptozotocinen_US
dc.titleRenoprotective Activity of Moringa Oleifera Lamk toward Kidney Injury Rats Induced by Streptozotocinen_US
dc.typeArticleen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record