| dc.contributor.author | WALUYO, Joko | |
| dc.contributor.author | WAHYUNI, Dwi | |
| dc.date.accessioned | 2021-04-29T07:00:22Z | |
| dc.date.available | 2021-04-29T07:00:22Z | |
| dc.date.issued | 2017-10-02 | |
| dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/104490 | |
| dc.description.abstract | Earthworm (Pheretima javanica K.) is a common soil biofertilizer. This repulsive animal for
some has been widely used for remedial medicine as well. Simplicia being used in this study was
obtained from dried and blended earthworm along with its intact internal organs. The aim of
the study was to determine the toxicity effect of earthworms powder to renal histopathology in
rats (Rattus norvegicus). A total of 50 rats were divided into five groups consisting of a negative
control group (2 ml 1% CMC Na), P1 earthworms group at dose of 0.4 grams, P2 earthworms
groups at dose of 0.8 grams, P3 earthworms group at a dose of 1.6 grams, and P4 earthworms
group at a dose of 3.2 grams. The rats were acclimated for about a week, then orally induced by
earthworm powder. The treatments were conducted for 14 consecutive days to see any toxic
symptoms developed. ANOVA results showed the administration of earthworm (Pheretima
javanica K.) powder did not significantly affect renal physiology and histopathology. There was
no damage observed microscopically. | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Bioedukasi Jurnal Biologi dan Pembelajarannya | en_US |
| dc.subject | Pheretima javanica K. powder | en_US |
| dc.subject | ,Rattus norvegicus B. | en_US |
| dc.subject | renal histopathology. | en_US |
| dc.title | Acute Toxicity of Earthworm (Pheretima javanica K.) Powder on Renal Histopathological Description of Rat (Rattus norvegicus B.) | en_US |
| dc.type | Article | en_US |
| dc.identifier.kodeprodi | KODEPRODI0210103#PendidikanBiologi | |
| dc.identifier.nidn | NIDN0028105707 | |
| dc.identifier.nidn | NIDN0009036001 | |
