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    SINTESIS 1-(4-NITROBENZOILOKSIMETIL)-5- FLUOROURASIL SEBAGAI PENGEMBANGAN OBAT KANKER

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    Mayasari (092210101055)_1.pdf (61.72Kb)
    Date
    2013-12-12
    Author
    Mayasari Kurnia N. D.
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    Abstract
    ABSTRAK 1-(4-nitrobenzoiloxymethyl)-5-fluorouracil were synthesized from a lead compound 5-fluorouracil (5FU), an anticancer commonly used for treating breast cancer. The compound were synthesized by two steps, the substitution of hydroxymethyl to N1 position of 5-FU followed by esterification by 4- nytrobenzoilcloride. The product were purified by coloumn chromatography and identified by 1HNMR and FTIR-KBr. The purity was characterized by TLCDensitometry and its melting point range. Finally, the compound was synthesized successfully.
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    http://repository.unej.ac.id/handle/123456789/8663
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    • UT-Faculty of Pharmacy [1514]

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    UPA-TIK Copyright © 2024  Library University of Jember
    Contact Us | Send Feedback

    Indonesia DSpace Group :

    University of Jember Repository
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    UIN Syarif Hidayatullah Institutional Repository