Optimasi Carbopol Dan Propilen Glikol Dalam Formulasi Sediaan Gel Tabir Surya Ekstrak Etanol Buah Mengkudu
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Fakultas Farmasi
Abstract
Excessive exposure to ultraviolet (UV) radiation can cause skin damage,
necessitating protection in the form of sunscreen. Noni fruit (Morinda citrifolia L.) is
known to contain secondary metabolites, such as flavonoids and phenolics, which have
potential as antioxidants and sunscreens. This study aims to determine the optimum
composition of carbopol as a gelling agent and propylene glycol as a humectant in the
sunscreen gel formulation of noni fruit ethanolic extract. The optimization method
employed is Factorial Design with two factors and two levels: carbopol concentrations
(0.5% and 2%) and propylene glycol concentrations (5% and 15%). The tested
response parameters include organoleptic properties, homogeneity, pH, spreadability,
adhesion, and viscosity. The results are expected to yield an optimum formula that
meets the physical property requirements of the gel and provides maximum UV
protection effectiveness. The results showed that variations in carbopol and propylene
glycol concentrations affected the physical properties of the sunscreen gel. The
optimum formulation had a carbopol concentration of 1,959% and a propylene glycol
concentration of 10,515%.
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Finalisasi 28 Juli 2026 Rudi H
