| dc.contributor.author | Mayasari Kurnia N. D. | |
| dc.date.accessioned | 2013-12-17T02:15:19Z | |
| dc.date.available | 2013-12-17T02:15:19Z | |
| dc.date.issued | 2013-12-17 | |
| dc.identifier.nim | NIM092210101055 | |
| dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/9316 | |
| dc.description.abstract | ABSTRAK
1-(4-nitrobenzoiloxymethyl)-5-fluorouracil were synthesized from a lead
compound 5-fluorouracil (5FU), an anticancer commonly used for treating breast
cancer. The compound were synthesized by two steps, the substitution of
hydroxymethyl to N1 position of 5-FU followed by esterification by 4nytrobenzoilcloride.
The product were purified by coloumn chromatography and
identified by
1
HNMR and FTIR-KBr. The purity was characterized by TLCDensitometry
and
its
melting
point
range.
Finally,
the
compound
was
synthesized
successfully. | en_US |
| dc.language.iso | other | en_US |
| dc.relation.ispartofseries | 092210101055; | |
| dc.subject | 1-4-nitrobenzoyloxymethyl-5-fluorouracil 5-fluorouracil anticancer benzoylation | en_US |
| dc.title | SINTESIS 1-(4-NITROBENZOILOKSIMETIL)-5FLUOROURASIL SEBAGAI PENGEMBANGAN OBAT KANKER | en_US |
| dc.type | Other | en_US |
