Hubungan Indeks Mentzer Dengan Kadar Feritin Pada Ibu Hamil Sebagai Biomarker Skrining Anemia Defisiensi Besi

Abstract

Iron deficiency anemia is a significant global health problem, especially in developing countries. The prevalence of anemia in pregnant women, according to the Jember District Health Office in 2023, reached 21.28%. This condition poses risks to the health of the mother, fetus, and child. Early assessment of anemia during pregnancy is crucial to prevent health complications. Ferritin testing can help diagnose anemia, but its values may be affected by other factors. The Mentzer Index is a formula used to assist in this diagnosis, calculated by dividing the average volume of red blood cells (MCV) by the number of erythrocytes. The purpose of this study was to determine the relationship between the Mentzer Index and ferritin levels in pregnant women as a biomarker of iron deficiency anemia screening. This study is an observational analytic study with a cross-sectional design. Sampling was done with a simple random sampling technique, and 33 samples of pregnant women were obtained. Data were collected by taking blood samples and conducting interviews using a questionnaire. The results of data analysis using the Spearman test showed a moderate negative correlation between the Mentzer Index and ferritin levels. The p-value was recorded as 0.038, with an r-value of -0.363. These results indicate that the higher the Mentzer Index, the lower the ferritin levels. The conclusion of this study is that there is a significant relationship between Mentzer Index values and ferritin levels in pregnant women as a biomarker of iron deficiency anemia screening.