| dc.description.abstract | Shigella dysenteriae is bacteria that caused diarrhea with high morbidity and mortality.
Resistance and toxicity has reported in some antibiotics therapy towards S. dysentriae.
Therefore, alternative therapy based on herbal plants is needed. Chymbopogon citratus oil
can be used as an antibacterial to Escherichia coli, Klebsiella pneumoniae, Streptococcus
mutans, all strains Staphlylococcus sp, Bacillus cereus and Bacillus subtilis. This study
aimed to investigate antibacterial activity of C. citratus oils on the growth of S. dysentriae
and its minimum inhibitory concentration (MIC). This type of research was a quasi
experimental. Antibacterial activity test performed by diffusion method. Subjects in this
study were S. dysentriae. C. citratus oil concentration used were 15 µl/ml, 20 µl/ml, 25
µl/ml, 30 µl/ml, 35 µl/ml and 40 µl/ml. Positive control group was given ciprofloxacin 5 µl/ml
and a negative control group was given tween-80. Inhibition zone was observed at a
concentration of 25 µl/ml (P3). The MIC of C. citratus oils againts S. dysentriae was at a
concentration of 25 µl/ml. Kruskal Wallis analysis showed that p=0.000 and α=0.05, it was
revealed that there were differences between antibacterial activity amoung tested group
with different concentration. | en_US |
