• Login
    View Item 
    •   Home
    • LECTURER SCIENTIFIC PUBLICATION (Publikasi Ilmiah)
    • LSP-Jurnal Ilmiah Dosen
    • View Item
    •   Home
    • LECTURER SCIENTIFIC PUBLICATION (Publikasi Ilmiah)
    • LSP-Jurnal Ilmiah Dosen
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    The Effect of Vitamin C towards Endothelial Dysfunction in CdCl2 -induced HUVEC Culture

    Thumbnail
    View/Open
    F. K_Jurnal_Kristianningrum_The Effect of Vitamin C.pdf (187.4Kb)
    Date
    2018-05-22
    Author
    Sofiana, Kristianingrum Dian
    Prihardina, Bunga
    Khotimah, Husnul
    Widodo, Muhammad Aris
    Metadata
    Show full item record
    Abstract
    Cardiovascular diseases are the leading cause of death globally which usually begins with endothelial dysfunction. This vascular abnormality is potentially caused by one kind of heavy metal called cadmium . HUVEC was induced by 24.154 µg/L CdCl 2. Three treatment groups of CdCl -induced HUVEC were employed, each given vitamin C concentrations of 50, 100, and 200 µM, respectively. Cell viability was assessed by MTT assay. Levels of NO and MDA were determined by with the calorimetric test. Cell viability was increased significantly in treatment group receiving vitamin C 100 and 200 µM. However, there were no significant differences on NO and MDA levels in vitamin C treatment groups compared to control. In conclusion, vitamin C increases endothelial cell viability and NO level, and reduces MDA levels in CdCl 2 -induced HUVEC. This study implies the importance of vitamin C supplementation to prevent cardiovascular diseases.
    URI
    http://repository.unej.ac.id/handle/123456789/85753
    Collections
    • LSP-Jurnal Ilmiah Dosen [7369]

    UPA-TIK Copyright © 2024  Library University of Jember
    Contact Us | Send Feedback

    Indonesia DSpace Group :

    University of Jember Repository
    IPB University Scientific Repository
    UIN Syarif Hidayatullah Institutional Repository
     

     

    Browse

    All of RepositoryCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    UPA-TIK Copyright © 2024  Library University of Jember
    Contact Us | Send Feedback

    Indonesia DSpace Group :

    University of Jember Repository
    IPB University Scientific Repository
    UIN Syarif Hidayatullah Institutional Repository