| dc.contributor.author | Roshida, Anindya | |
| dc.contributor.author | Robin, Dwi Merry Christmarini | |
| dc.contributor.author | Corvianindya, Yani | |
| dc.date.accessioned | 2017-07-28T06:53:40Z | |
| dc.date.available | 2017-07-28T06:53:40Z | |
| dc.date.issued | 2017-07-28 | |
| dc.identifier.isbn | 978-602-61803-1-5 | |
| dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/80488 | |
| dc.description | Prosiding The 4th Dentistry Scientific Meeting of Jember 2017 “Improving Competency in Dentistry” | en_US |
| dc.description.abstract | Background: The formation of prostaglandins and thromboxane in temporomandibular joint
osteoarthritis trigger the production of pro-inflammatory cytokines that can degrade extracellular
matrix and cause the number of chondrocytes decreased. Lemuru fish oil (Sardinella longiceps) are
anti-inflammatory and may affect the number of chondrocytes. Purpose: To determine the potency of
lemuru fish oil to the number of temporomandibular joint chondrocytes in osteoarthritis rats. Methods:
36 rats were injected intraarticularly by CFA on the right of the temporomandibular joint. Four weeks
after injection, rats were given saline (K(-)), piroxicam (K(+)), and lemuru fish oil (P). Rats were
sacrificed on day 7, 14, and 21. The number of chondrocytes was calculated in mature zone with HE
staining. Result: There was increasing number of chondrocytes significantly in treatment group
compared with negative or positive control group on day 14 and 21. Conclusion: Lemuru fish oil
(Sardinella longiceps) can inhibit inflammation like piroxicam and may improve the number of
temporomandibular joint chondrocytes in rats with osteoarthritis. | en_US |
| dc.language.iso | id | en_US |
| dc.subject | fish oil | en_US |
| dc.subject | osteoarthritis | en_US |
| dc.subject | the number of chondrocytes | en_US |
| dc.title | Potensi Minyak Ikan Lemuru (Sardinella longiceps) terhadap Jumlah Kondrosit Sendi Temporomandibula Tikus Osteoartritis | en_US |
| dc.type | Prosiding | en_US |
