| dc.description.abstract | Introduction. Robusta coffee bioactive component such as flavonoids,
xanthine can serve as anti-inflammatory, antibacterial. It is expected can
provide solutions as an immunomodulator to dental caries. Currently
immunomodulatory become an important topic in the world to prevent and treat
disease. Inflammation is one of the immune response is important in dental
caries. whereas one of dental caries theraphy is pulp capping. Aim. analyze the
inflammatory response Robusta coffee beans to dental caries. Method. which
are divided into 5 groups. KO: the group made a hole in the tooth, KP1; the
group made a hole in the tooth + pulpcaping Ca(OH)2, KP2: a hole in the tooth
+ pulpcapping with coffee bean paste fillings 25%, KP3: a hole in the tooth +
pulpcapping with coffee bean paste fillings 50%, KP4: a hole in the tooth +
pulpcapping with coffee bean paste fillings 75%. Days to 7, 14, 21 made the
rats were sacrificed for the preparation of the pulp for analysis of inflammatory
cells with HE staining. Result. ANOVA followed LSD test results showed
significant differences between groups. Noticeably higher concentration of
robusta coffee beans, then progressively decrease the number of inflammatory
cells. Conclusion. Robusta coffee beans decrease inflammation in dental caries. | en_US |
