| dc.contributor.author | Nuri | |
| dc.contributor.author | Wiwien Sugih Utami | |
| dc.contributor.author | Yunita Armiyanti | |
| dc.date.accessioned | 2014-07-14T05:03:37Z | |
| dc.date.available | 2014-07-14T05:03:37Z | |
| dc.date.issued | 2014-07-14 | |
| dc.identifier.isbn | 978-602-9030-08-2 | |
| dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/58313 | |
| dc.description | INTERNATIONAL CONFERENCE ON HALAL SCIENCE & TECHNOLOGY 2012
DENPASAR, BALI, INDONESIA JULY 4-6, 2012 | en_US |
| dc.description.abstract | Tithonia diversifolia (Hemsley) A. Gray has been used traditionally to treat malaria. The
results of previous study showed that ethanolic extract of this leaves had antimalarial activity
in vivo with ED
of 113.39 mg/kg. This study aims to fractionated of crude ethanolic extract
of T. diversifolia leaves to obtaine terpenoide-rich fraction and to assay it’s antimalarial
activity in mice that infected with Plasmodium berghei. Fractionation was conducted by
vacuum liquid chromatography using silica gel 60 as stationary phase, and n-hexane,
chloroform, methanol as mobile phase. The Antimalarial activity assay carried out using 4day
suppression test. Antimalarial activity assay results indicate that the terpenoide-rich
fraction could inhibit the growth of P. berghei ED50 of 5.058 mg/kgBW . | en_US |
| dc.language.iso | other | en_US |
| dc.subject | Tithonia diversifolia, terpenoide-rich fraction, malaria | en_US |
| dc.title | In Vivo Antimalarial Activity of Terpenoid-Rich Fraction of Ethanolic Extract of Tithonia diversifolia (Hemsley) A. Gray Leaves | en_US |
| dc.type | Article | en_US |
