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dc.contributor.authorNuri
dc.contributor.authorUtami, Wiwien Sugih
dc.contributor.authorArmiyanti, Yunita
dc.date.accessioned2014-02-12T04:09:03Z
dc.date.available2014-02-12T04:09:03Z
dc.date.issued2014-02-12
dc.identifier.isbn978-602-9030-08-2
dc.identifier.urihttp://repository.unej.ac.id/handle/123456789/27403
dc.descriptionINTERNATIONAL CONFERENCE ON HALAL SCIENCE & TECHNOLOGY 2012 DENPASAR, BALI, INDONESIA JULY 4-6, 2012en_US
dc.description.abstractTithonia diversifolia (Hemsley) A. Gray has been used traditionally to treat malaria. The results of previous study showed that ethanolic extract of this leaves had antimalarial activity in vivo with ED of 113.39 mg/kg. This study aims to fractionated of crude ethanolic extract of T. diversifolia leaves to obtaine terpenoide-rich fraction and to assay it’s antimalarial activity in mice that infected with Plasmodium berghei. Fractionation was conducted by vacuum liquid chromatography using silica gel 60 as stationary phase, and n-hexane, chloroform, methanol as mobile phase. The Antimalarial activity assay carried out using 4day suppression test. Antimalarial activity assay results indicate that the terpenoide-rich fraction could inhibit the growth of P. berghei ED50 of 5.058 mg/kgBW .en_US
dc.language.isootheren_US
dc.subjectTithonia diversifolia, terpenoide-rich fraction, malariaen_US
dc.titleIn Vivo Antimalarial Activity of Terpenoid-Rich Fraction of Ethanolic Extract of Tithonia diversifolia (Hemsley) A. Gray Leavesen_US
dc.typeArticleen_US


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