dc.contributor.author | Ifada | |
dc.date.accessioned | 2013-12-03T02:50:39Z | |
dc.date.available | 2013-12-03T02:50:39Z | |
dc.date.issued | 2013-12-03 | |
dc.identifier.nim | 082210101047 | |
dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/2700 | |
dc.description.abstract | A new compound from 5-fluorouracil (5-FU) derivatives, 1-(4-
methoxybenzoyloxymethyl)-5-fluorouracil has been synthesized in a two steps
reaction, alkylation (5-FU and formaldehyde to form 1-hydroxymethyl-5-
fluorouracil) and esterification (1-hydroxymethyl-5-fluorouracil and 4-
methoxybenzoylchloride to form 1-(4-methoxybenzoyloxymethyl)-5-fluorouracil).
Reaction product purified by chromatography column, the product has been
characteryzed for physical apperance is a yellowish white, crystal and melting range
168-169OC. Based on the FTIR and 1H-NMR spectra, it showed that the purified
product does not contain a single compound. This fact is supported by Thin Layer
Chromatography (TLC) result showing two spots for the pressure of 1-(4-
methoxybenzoyloxymethyl)-5-fluorouracil and 4-methoxybenzoate acid. | en_US |
dc.relation.ispartofseries | 082210101047; | |
dc.subject | 5-fluorouracil derivates, anticancer, 1-(4-methoxybenzoyloxymethyl)-5- fluorouracil, benzoylation | en_US |
dc.title | Sistensis 1-(4-Metoksibenzoiloksimetil)-5-Fluorourasil Sebagai Upaya Pengembagan Obat Antikanker | en_US |
dc.type | Other | en_US |