Influence of chronic pesticide exposure on malondialdehyde and 8-OHdG levels among Wuluhan farmers, Jember, Indonesia: a cross-sectional study

dc.contributor.author	R. M. PUTRI, Elvia
dc.contributor.author	SADEWA, Ahmad H.
dc.contributor.author	SUPANGAT, Supangat
dc.date.accessioned	2025-11-04T03:21:07Z
dc.date.available	2025-11-04T03:21:07Z
dc.date.issued	2025-10-25
dc.identifier.uri	https://repository.unej.ac.id/xmlui/handle/123456789/128536
dc.description.abstract	Chronic pesticide exposure causes oxidative stress and DNA damage in humans, with long-term health implications. This study aims to assess chronic pesticide exposure with oxidative stress and DNA damage biomarkers among farmers in Wuluhan District, Jember, Indonesia. Methods Seventy-four farmers from two villages in Wuluhan, Jember, were interviewed regarding pesticide exposure using a questionnaire, and serum MDA and urine 8-OHdG were examined. Thirty-six subjects from the first village had low-moderate intensity, and 38 subjects from the second village had high spraying intensity before the test. Data were analyzed by Spearman correlation tests between the chronic pesticide exposure index, MDA serum, and urinary 8-OHdG in each group.	en_US
dc.language.iso	other	en_US
dc.publisher	BMC Pharmacology and Toxicology	en_US
dc.subject	8-OHdG	en_US
dc.subject	DNA damage	en_US
dc.subject	MDA	en_US
dc.subject	Oxidative stress	en_US
dc.subject	Pesticide exposure	en_US
dc.title	Influence of chronic pesticide exposure on malondialdehyde and 8-OHdG levels among Wuluhan farmers, Jember, Indonesia: a cross-sectional study	en_US
dc.type	Article	en_US