| dc.description.abstract | Tooth extraction can cause wound in hard tissue and soft tissue inside oral cavity. Wound healing
process involves cell proliferation especially fibroblast cells. To accelerate fibroblast cell proliferation
alternative substance that can accelerates wound healing process is needed which is arabica coffee fruit skin.
Arabica coffee fruit skin contains substances such as polyphenols, tannin, chlorogenic acid, and caffeine
expected to be able to stimulate fibroblast cells amount. Objective: To understand arabica coffee fruit skin
potential towards increase in number of fibroblast cells on the socket after tooth extraction. Method: The design
of this research was post test only control group with sample size of 24 wistar mouse. The samples used were
divided into two groups which are control and treatment group. Then treatment was given in 3 days, 5 days, and
7 days. Then they were decapitated to undergo tissue processing with HE coloring and post tooth extraction
socket fibroblast cells counting. Acquired data then analyzed used One Way ANOVA and LSD test. Result:
Fibroblast cell amount increased significantly (p<0.05) in treatment group compared to control group.
Conclusion: Arabica coffee fruit skin potentially increase fibroblast cells amount in socket post tooth extraction
of male wistar mouse. | en_US |
