Secondary Metabolite Isolation From Indonesian Folious Lichen: Phyloporon Aciculare (ACH.)
dc.contributor.author | PUTRI, C. P. Z. S. | |
dc.contributor.author | LAKSONO, T. A. | |
dc.contributor.author | PRATOKO, D. K. | |
dc.contributor.author | TRIATMOKO, B. | |
dc.contributor.author | PRATAMA, A. N. W. | |
dc.contributor.author | SISWOYO, T. A. | |
dc.contributor.author | UNTAR, L. F. | |
dc.contributor.author | Wongso, H. | |
dc.contributor.author | HENDRA, R. | |
dc.contributor.author | KELLER, P. A. | |
dc.contributor.author | NUGRAHA, A. S. | |
dc.date.accessioned | 2023-03-30T06:57:08Z | |
dc.date.available | 2023-03-30T06:57:08Z | |
dc.date.issued | 2022-12-03 | |
dc.identifier.uri | https://repository.unej.ac.id/xmlui/handle/123456789/114115 | |
dc.description.abstract | Lichen has been investigated for discovering new antibacterial agents. Although Indonesia is considered one of the megadiverse countries and a home to a diverse array of lichen species, research on lichens for medicinal properties remains scarce. In this study, an intensive semi-preparative High-Performance Liquid Chromatography successfully isolated a major compound from Phyloporon aciculare, with its molecular structure proposed as methyl 2,4- dihydroxy-3,6-dimethylbenzoate by Nuclear Magnetic Resonance spectral and was confirmed by Mass Spectrometry data analysis. The crude extract of the lichen possessed a selective antibacterial activity in which significantly inhibited Kocuria rhizophila by 96.9% at a 100 µg/mL concentration. In addition, previous reports on methyl 2,4-dihydroxy3,6-dimethylbenzoate from other species indicated the compound to have antibacterial, anti-inflammatory, and anticancer activities. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Rasayan Journal of Chemistry | en_US |
dc.subject | Phyloporon aciculare | en_US |
dc.subject | Depside | en_US |
dc.subject | Antibacterial | en_US |
dc.subject | Atraric Acid | en_US |
dc.subject | Lichen | en_US |
dc.title | Secondary Metabolite Isolation From Indonesian Folious Lichen: Phyloporon Aciculare (ACH.) | en_US |
dc.type | Article | en_US |
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