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dc.contributor.authorPUTRI, C. P. Z. S.
dc.contributor.authorLAKSONO, T. A.
dc.contributor.authorPRATOKO, D. K.
dc.contributor.authorTRIATMOKO, B.
dc.contributor.authorPRATAMA, A. N. W.
dc.contributor.authorSISWOYO, T. A.
dc.contributor.authorUNTAR, L. F.
dc.contributor.authorWongso, H.
dc.contributor.authorHENDRA, R.
dc.contributor.authorKELLER, P. A.
dc.contributor.authorNUGRAHA, A. S.
dc.date.accessioned2023-03-30T06:57:08Z
dc.date.available2023-03-30T06:57:08Z
dc.date.issued2022-12-03
dc.identifier.urihttps://repository.unej.ac.id/xmlui/handle/123456789/114115
dc.description.abstractLichen has been investigated for discovering new antibacterial agents. Although Indonesia is considered one of the megadiverse countries and a home to a diverse array of lichen species, research on lichens for medicinal properties remains scarce. In this study, an intensive semi-preparative High-Performance Liquid Chromatography successfully isolated a major compound from Phyloporon aciculare, with its molecular structure proposed as methyl 2,4- dihydroxy-3,6-dimethylbenzoate by Nuclear Magnetic Resonance spectral and was confirmed by Mass Spectrometry data analysis. The crude extract of the lichen possessed a selective antibacterial activity in which significantly inhibited Kocuria rhizophila by 96.9% at a 100 µg/mL concentration. In addition, previous reports on methyl 2,4-dihydroxy3,6-dimethylbenzoate from other species indicated the compound to have antibacterial, anti-inflammatory, and anticancer activities.en_US
dc.language.isoenen_US
dc.publisherRasayan Journal of Chemistryen_US
dc.subjectPhyloporon aciculareen_US
dc.subjectDepsideen_US
dc.subjectAntibacterialen_US
dc.subjectAtraric Aciden_US
dc.subjectLichenen_US
dc.titleSecondary Metabolite Isolation From Indonesian Folious Lichen: Phyloporon Aciculare (ACH.)en_US
dc.typeArticleen_US


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