dc.contributor.author | DHARMAYANTI, Agustin Wulan Suci | |
dc.contributor.author | ANJANI, Ajeng Nurwahyuningtyas | |
dc.contributor.author | HANDAYANI, Ari Tri Wanodyo | |
dc.contributor.author | HAMZAH, Zahreni | |
dc.contributor.author | MEILAWATY, Zahara | |
dc.contributor.author | NOVITA, Masniari | |
dc.contributor.author | SYAFRIADI, Mei | |
dc.contributor.author | SHITA, Amandia Dewi Permana | |
dc.date.accessioned | 2021-08-25T00:35:50Z | |
dc.date.available | 2021-08-25T00:35:50Z | |
dc.date.issued | 2021-07-23 | |
dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/105110 | |
dc.description.abstract | The ovaries represent the female reproductive organs that determine the women's fertility status and their
systemic and oral health, correlating to sex steroid hormone alteration. This study aimed to investigate the
effect of cassava leaves extract treatment to SOD expression in the animal model-ovaries after Porphyromonas
gingivalis injection. 15 female Sprague Dawley rats were used and divided into five groups: (1) control without
cassava leaves extract treatment (C); (2) P. gingivalis without cassava leaves extract treatment (T1); (3) P.
gingivalis and cassava leaves extract (T2); (4) P. gingivalis and vitamin C (T3); and (5) P. gingivalis and
metronidazole (T4). Animal were euthanised at day seven after the initial treatment to collect ovaries. The
ovaries sections were immunohistochemically stained to quantify SOD expression using light microscope while
the Image J software was used to quantify the SOD expression. The results showed that all of the follicle types
had the same intensity of SOD expression. Most of the follicles exhibited low intensity of SOD expression,
except for atretic follicles. In conclusion, P. gingivalis and cassava leaves extract influenced SOD expression in
the ovaries of animal models, which increased the SOD expression | en_US |
dc.language.iso | en | en_US |
dc.publisher | Ann Dent UM | en_US |
dc.subject | Cassava Leaves Extract | en_US |
dc.subject | Ovarian | en_US |
dc.subject | P. gingivalis | en_US |
dc.subject | Superoxide dismutase (SOD) | en_US |
dc.title | Superoxide Dismutase Expression in the Ovaries of Periodontitis Animal Models Induced by Porphyromonas gingivalis and Treated with Cassava Leaves Extract | en_US |
dc.type | Article | en_US |
dc.identifier.kodeprodi | KODEPRODI1610101#Kedokteran Gigi | |
dc.identifier.nidn | NIDN0018087303 | |
dc.identifier.nidn | NIDN0001046111 | |
dc.identifier.nidn | NIDN0027058005 | |
dc.identifier.nidn | NIDN0025116803 | |
dc.identifier.nidn | NIDN0029056802 | |
dc.identifier.nidn | NIDN0003068006 | |
dc.identifier.nip | NIP197908142008122003 | |