| dc.description.abstract | Avocado leaves (Persea americana Mill.) historically used as a herbal
medicine used to ease the expense of urine and crushed a kidney stone in the urinary
tract. Avocado leaves contain sugar, d-parseit, quercetin, flavonoids, and compounds
sterin. The availability of avocado leaves in the society becames a great opportunity
to be utilized as a herbal medicine, it is unknown yet whether the avocado leaves
extract was able to decrease edema glomerulus and cell damage in the kidneys. The
aim of this research knew the effect of ethanol extract of avocado leaves to decrease
edema glomerulus and cell damage kidney of white rat. The research method used
The Post Test Only Control Group Design. The dose was 100 mg/0.2kg bw, 200
mg/0.2kg bw, 300 mg/0.2kg bw, with inducer (ethylene glycol + ammonium chloride)
as positive control, the treatment carried out during 10 days. Data analysis used
Anova. The results showed for parameter damage the glomerulus with (F = 4.931, p
= 0.027, < 0.05) which means there was the effect of the ethanol extracts of avocado
leaves significantly to decrease edema glomerulus, while parameters proximal tubule
damage with (F = 5.755, p = 0.018, < 0.05) which means there was the effect of the
ethanol extracts of avocado leaves significantly to decrease cell damage kidney white
rat. The dose of ethanol extract of avocado leaves which are most effective against the
decrease of edema glomerulus was 100 mg/0.2kg bw and cell damage kidney white
rat was 200 mg/0.2kg bw. | en_US |
