Show simple item record

dc.contributor.authorKURNIAWATI, Atik
dc.contributor.authorPRAHARANI, Depi
dc.contributor.authorHANDOKO, Grace Valencia
dc.date.accessioned2020-11-02T05:45:23Z
dc.date.available2020-11-02T05:45:23Z
dc.date.issued2020-07-01
dc.identifier.urihttp://repository.unej.ac.id/handle/123456789/101529
dc.description.abstractIntroduction: Porphyromonas gingivalis adhesion to neutrophils is an important initial process in periodontal disease. The process of bacterial adhesion must be inhibited so that periodontal disease does not develop into severe. Graptophyllum pictum contains several active substances that can affect the function of neutrophils. Aim of the research to find out the inhibition of Graptophyllum pictum leaf extracts (GLE) in various concentrations against the adhesion of Porphyromonas gingivalis to neutrophils. Methods: The method used is experimental laboratory using the post test only control group design. This research used a sample of isolate neutrophils taken from the blood of subjects with inclusion criteria. The sample was divided into 5 groups: the control group (without GLE), GLE 3.125%, GLE 6.25%, GLE 12.5%, and GLE 25%.The neutrophils isolate was incubated with GLE for 3 hours, then exposed to Porphyromonas gingivalis for 8 hours. The adhesion index is calculated by the average number of Porphyromonas gingivalis attached to 100 neutrophils. Results: Based on these results can be interpreted that GLE 3.125%, GLE 6.25% and GLE 12.5% showed no significant difference, in the mean those concentrations doesn’t have ability to inhibit the adhesion of Porphyromonas gingivalis in neutrophils. So GLE 25% only which is able to inhibit the adhesion of Porphyromonas gingivalis in neutrophils. Conclusion: GLE can inhibit the adhesion of Porphyromonas gingivalis to neutrophils by GLE 25% effectively only.en_US
dc.language.isoenen_US
dc.publisherMalaysian Journal of Medicine and Health Sciences, 16(SUPP4): 60-66, July 2020en_US
dc.subjectAdhesionen_US
dc.subjectGraptophyllum pictum (L) Griffen_US
dc.subjectPorphyromonas gingivalisen_US
dc.subjectneutrophilsen_US
dc.titleEffectiveness of Graptophyllum pictum (L.) Griff Leaves Extract Toward Porphyromonas gingivalis Adhesion to Neutrophilsen_US
dc.typeArticleen_US
dc.identifier.kodeprodiKODEPRODI1610101#Kedokteran Gigi
dc.identifier.nidnNIDN0004027108
dc.identifier.nidnNIDN0022016801


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record