|dc.description.abstract||Background: Tooth extraction is tooth removal procedure from the alveolar
socket. Tooth extraction causes wounds in the form of exposed alveolar bone
to the oral cavity where the treatment should be observed. Wound healing is
begun by an inflammatory phase. The first defense cells that come to the
wound tissue are neutrophils. The excessive post-traumatic inflammation can
cocoa bean extract,
lead neutrophils to be overactivated. This condition may prolong and aggravate
the inflammatory response. This study is to determine the effect of cocoa seed
extract gel to the number of neutrophil.
Method: This research was an experimental research laboratories with the post
test control group design. 24 male Wistar rats were used to be the sample. The
sample were divided into 2 groups which were control and treatment group.
Cocoa seed extract gel was given to the treatment group, whereas the control
group didnt given the cocoa seed extract gel. The treatment and control groups
were performed decaputation on the 1st, 3rd, and 7th days after tooth
extraction. After decaputation was performed, socket tissue was taken to make
histological preparation which was stained by Hematoxylin Eosin.
Result: The neutrophils average of the treatment group is lower than control
group in the 1st, 3rd, and 7th day.
Conclusion: The result of the study showed that the 8% cocoa (Theobroma
cacao L.) bean gel extract could reduce the neutrophils in rat post-extraction