SINTESIS DAN AKTIVITAS ANTIOKSIDAN 3-(3,4-dimetoksifenil)-1-(4-metilfenil)-2-propen-1-on
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Date
2016-09-26Author
Pangaribowo, Dian Agung
Sary, Indah Purnama
Pratoko, Dwi Koko
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Show full item recordAbstract
A new compound from chalcone derivate has been synthesized from 4-methylacetophenone and 3,4dimethoxybenzaldehyde
by
Claisen-Schmidt
condensation
with
catalyst
of
NaOH
60%.
This
compound
is
3-(3,4dimethoxyphenyl)-1-(4-methylphenyl)-2-propen-1-one.
Structureelucidation
was
conducted
by FTIR
and
H-NMR
analysis. The compound is relatively pure and this can be identified by only one spot on TLC analysis and the range
of melting point is narrow. Antioxidant activity evaluation of the compound with DPPH method showed that IC
50
is
455.312 ppm, lower than vitamin C as the standard.
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- LSP-Jurnal Ilmiah Dosen [7287]