Healing Effects of Fresh Earthworms (Pheretima Javanica K.) for Typhoid Fever Induced in Male White Rat (Rattus Norvegicus L.)

Abstract

Typhoid fever is systemic infectious disease caused by Salmonella typhi bacteria which is still considered as a health problem for the world people. This reasearch aims to know the healing efffects of fresh earthworm species Pheretima javanica to reduction typhoid fever replace the treatment using cloramphenicol. This research using male white rats (Rattus norvegicus L.) with negative control and positive control by using cloramphenicol. and 4 treatments group of each 5 rats. The test consists of Widal test, feces test and body weight measurement were analyzed descriptively, while body temperature measurement was analyzed by using ANOVA test and continued with Duncan test with confidence rate at 95%. The analyzed result got probably result p = 0,0001 (p < 0,05) means that fresh earthworm has a significant effect on the reduction of typhoid fever on male white rats with optimal dosage is 3 gram / 0.2 kg BB.