Please use this identifier to cite or link to this item:
https://repository.unej.ac.id/xmlui/handle/123456789/86218
Title: | The Improvement of TNF- α and Inflamation Cell on the Lungs Hypersensitivity Reaction becauses of Wood Dust Exposure |
Authors: | Ma'rufi, Isa Prahastuti, Anita Dewi Hartanti, Ragil Ismi |
Keywords: | Hypersensitivity Pneumonitis (HP) TNF-α, Inflamation Cell Dust from Paddy Milling |
Issue Date: | 5-Jul-2018 |
Abstract: | This research aimed to analyze the effect of wood dust on TNF-α on Mice blood (MusMusculus) BALB / C and to analyze the influence of wood dust on the number of inflammatory cells, ie macrophage, lymphocyte, neutrophil and mast cell in lung tissue of mice BALB / C, as well as explain the mechanism of lungs hypersensitivity reaction due to wood furniture dust exposure. The experimental laboratory research was conducted, and mice was become the animal experiment. The research design used was Randomized the posttest only control group design. Exposure was performed 4 hours a day with 2 hours length of exposure in the morning with 1 hour rest period in 6 times a week for 4 weeks at exposure space in a glass-shaped cube with a size of 20x20x20 cm 3 . Concentrations of wood furniture dust exposed were 0.50 mg / m3, 0.75 mg / m3, 1.00 mg / m3. The findings showed that (1) wood furniture dust exposure increased between experimental group compared with control group in mice (Musmusculus) BALB / C; (2) wood furniture dust exposure increased TNF, in lung tissue between experimental group compared with control group in mice (Musmusculus) BALB / C; and (3) wood furniture dust exposure increased mast cells, neutrophils, lymphocytes, and macrophages in lung tissue between experimental group compared with control group in mice (Musmusculus) BALB / C. |
Description: | Health Notions, Volume 2 Nomor 2 (Februari-Maret 2018) |
URI: | http://repository.unej.ac.id/handle/123456789/86218 |
ISSN: | 2580-4936 |
Appears in Collections: | LSP-Jurnal Ilmiah Dosen |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
F. KM_Jurnal_Isa Ma'rufi_The Improvement of TNF.pdf | 1.03 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.