ANGKA KEJADIAN LEKEMI DAN DUGAAN KUAT LEKEMI BEDASARKAN GAMBARAN LAB. PATOLOGI KLINIK R.S.U.D dr SOEBANDI JEMBER ( MEI 2000-DESEMBER 2004 )

Abstract

Abstract : Scientists and clinicians throughout the world have a special interest in Leukemia. For the scientists leukemic cells are usually procure in large numbers and in relative purity, and may in the future prove to have fundamental genetic changes that shed light on the pathogenesis of other forms of malignancy. For the clinician the disease in its many forms is fascinating in diagnosis and categorization and poses therapeutic challenges that can now be met gradually increasing success unfornately stastitics on the incidence, mortality and demographic charateristic of Leukemia are incomplete especially in RSUD dr. Soebandi Jember. Lekemi represent ferocity of disease which often at children. If diagnose lekemi can built early, the grade of expectation live patient will increase . The problem is being lifted in this research : how much incident patient of lekemi in RSUD dr. Soebandi Jember as Hospital Education of type of B. This research use criterion of sampel are based on period of May 2000 until December 2004. The aspect is being checked are gender, age, laboratory picture in the form of blood smear and bone marrow aspiration. From 576 patient which was evaluated their blood smear at period , there are 65 (11 %) suspect of leukemia, after the patient continued to bone marrow aspiration only equal to 13 (2%) patient. From 13 that patient, only 4 (0,7%) patient was diagnosed ALL, 1 (0,17 %) patient was diagnosed AML, and the other patient (1,4 %) was diagnosed hipoplastic anemia. The overall leukemia incidence rate in woman lower than man. The most of suspect patient leukemia was acute lekemi. The mean age of patients which suspect leukemia are 41-50 year’s old, while the mean age of patients leukemia among 31-40 and 41-50 year’s old. Almost all suspect of leukemia and entire patient of leukemia have anemia.The part of suspect of leukemia and entire patient of natural leukemia with lekositosis. All of patient with suspect acute leukemia have trombositopeni while the trombocyt number of patient with suspect chronic leukemia amount to normally , increased or decreased. All of patient leukemia have trombositopenia.Bone marrow examination is the golden standart to diagnosis leukemia, especially to classificated. The etiology of anemia and trombositopenia at patient very important to know before start theurapy.