Please use this identifier to cite or link to this item: https://repository.unej.ac.id/xmlui/handle/123456789/114123
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dc.contributor.authorHENDRA, Rudi-
dc.contributor.authorKHODIJAH, Rohimatul-
dc.contributor.authorALMURDANI, Muhammad-
dc.contributor.authorHARYANI, Yuli-
dc.contributor.authorNUGRAHA, Ari Satia-
dc.contributor.authorFRIMAYANTI, Neni-
dc.contributor.authorTERUNA, Hilwan Yuda-
dc.contributor.authorABDULAH, d Rizky-
dc.date.accessioned2023-03-30T07:11:07Z-
dc.date.available2023-03-30T07:11:07Z-
dc.date.issued2022-11-01-
dc.identifier.urihttps://repository.unej.ac.id/xmlui/handle/123456789/114123-
dc.description.abstractStenochlaena palustris (Burm.f.) Bedd. (Blechnaceae) or Kelakai is a traditional medicinal plant found in the Indonesian islands of Borneo and Sumatra. It has been used to treat wound healing, infection, and diabetes. Tis study looked into the free radical scavenging activity, antiplasmodial activity, toxicity, and antibacterial activity against pathogenic bacteria. Te species’ aerial part was extracted with methanol, followed by a liquid-liquid extraction against (n-hexane, dichloromethane, and ethyl acetate). Te extracts’ free radical scavenging activities were determined using DPPH and NO radicals. Te antiplasmodial and toxicity assays were conducted using two Plasmodium falciparum strains (3D7 and W2) and the brine shrimp lethality test. In addition, antibacterial activity was determined using the well difusion method. Te results revealed that ethyl acetate depicted potential activities toward the assay. Te ethyl acetate showed potential free radical scavenging activities with an IC50 value of 51.63±0.46 μg/mL (DPPH) and 60.03±0.65 μg/mL (NO). Te antiplasmodial activities showed that the ethyl acetate had potential activities among the extracts with an IC50 value of 11.06 ±0.45 μg/ mL. However, all the extracts demonstrated nontoxic toward Artemia salina with LC50>1000 μg/mL. Furthermore, the ethyl acetate demonstrated intermediate susceptibility against B. cereus ATCC 10876, V. parahaemolyticus ATCC 17802, L. monocytogenes ATCC 7644, and S. Typhimurium ATCC 14028 at a concentration of 500 μg/disc. According to these fndings, the ethyl acetate extract of S. palustris (Burm.f.) Bedd is a promising source of natural antioxidants and antiplasmodial agents.en_US
dc.language.isoenen_US
dc.publisherAdvances in Pharmacological and Pharmaceutical Sciencesen_US
dc.titleFree Radical Scavenging, Anti-Infectious, and Toxicity Activities from Stenochlaena palustris (Burm.f.) Bedd. Extractsen_US
dc.typeArticleen_US
Appears in Collections:LSP-Jurnal Ilmiah Dosen



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