USG guided-intra-articular platelet-rich plasma injection of knee-osteoarthritis patient

Abstract

Osteoarthritis is a degenerative joint disease with multiple risk factors. Knee osteoarthritis causes morning stiffness, movement restriction, and chronic-progressive pain of the knee joint. Osteoarthritis management aims to slow down disease progression and relieve pain and joint stiff ness. Its management includes non-pharmacological, pharmacological, and operative treatment. One therapeutic modality for osteoarthritis is intra-articular platelet-rich plasma (PRP) injection with an ultrasonography (USG) guide. In this case, PRP was made from the patient’s blood by centrifugation to obtain a highly concentrated sample1 of platelets. Platelets play a role in the healing process of osteoarthritis because they contain broad-spectrum growth factors. This scientific narrative report aims to prove the effectiveness of PRP management in patients with grade III knee-osteoarthritis. A 56 years old woman was diagnosed with 3rd-grade bilateral genu osteoarthritis. The patient underwent intra-articular PRP injection guided by Ultrasonography (USG). The procedure was performed on the right knee. A total of 2 procedures in 3 weeks. The patient came back 3 months later because of a relapse but with a lower pain score (VAS 4-5). The same procedure was carried out and evaluated a month later. The patient explained there were no pain experiences after the procedure even though no medicines were consumed during this period.