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Title: | The potential of toothpaste containing Robusta coffee bean extract in reducing gingival inflammation and dental plaque formation |
Authors: | PUJIASTUTI, Peni SAKINAH, Neira Najatus ARINA, Yuliana Mahdiyah Da’at WAHYUKUNDARI, Melok Aris PRAHARANI, Depi SARI, Desi Sandra |
Keywords: | gingivitis herbal toothpaste medicine Robusta coffee bean extract |
Issue Date: | 1-Jun-2023 |
Publisher: | Dental Journal (Majalah Kedokteran Gigi) |
Abstract: | The prevention of gingivitis using chemicals containing antibiotics and chlorhexidine can disrupt the balance of the oral microbiota and have side effects in long-term use. A recent development in the prevention of gingivitis is the use of natural ingredients. Coffee is a natural ingredient that compounds several antibacterial and anti-inflammation properties. Purpose: The study aimed to determine the potential of toothpaste containing Robusta coffee bean extract in reducing gingival inflammation and inhibiting the formation of dental plaque. Methods: Twenty male Rattus norvegicus were divided into four groups, namely the control group and treatment groups (TG) TG25%, TG50%, and TG75%. All groups were fitted with ligature wire on the first left molar to accumulate dental plaque. After the fourth day, the ligature wire was removed, and the TG25%, TG50%, and TG75% groups were brushed once a day using toothpaste containing various concentrations of Robusta coffee extract, while the control group was brushed without using toothpaste. Plaque index, gingival index, and interleukin-1 (IL-1) expression were observed on the fifth day. The data was statistically tested using a one-way analysis of variance and post hoc least significant difference. Results: The statistical test showed that the TG75% group had the lowest value of plaque, gingival index, and IL-1 expression, while the control group had the highest (p < 0.05). Conclusion: Robusta coffee bean extract toothpaste has the potential to reduce gingival inflammation and dental plaque formation in a rat with gingivitis. The most effective concentration of Robusta coffee bean extract toothpaste in reducing gingival inflammation and dental plaque formation was 75%. |
URI: | https://repository.unej.ac.id/xmlui/handle/123456789/112407 |
Appears in Collections: | LSP-Jurnal Ilmiah Dosen |
Files in This Item:
File | Description | Size | Format | |
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FKG_The potential of toothpaste containing Robusta coffee bean.pdf | 954.17 kB | Adobe PDF | View/Open |
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