Communication-An Optical Fiber Biosensor Based on a Lab-On-a Tip Approach for User Friendly Carbosulfan Detection in Vegetable Sample

Abstract

The search for new materials or platforms to be integrated into sensing design and devices is an interesting topic in sensor development, particularly a user-friendly and integrated device that no need for sample treatment and expertise. For this purpose, a pipette tip can be used as a novel approach in sensor development. For example, a pipette tip was developed as a pool optode for Hg (II) ions sensing.1 A pipette tip containing amine-functionalized sol-gel to enrich and purify phosphopeptides called a “lab-in-apipet-tip” was employed for mass spectroscopy measurements.2 Furthermore, a pipette tip was used as a lab-on-a-tip to create an electroanalysis system for Cu(II) ions detection.3 Here, a pipette tip can provide a sensing system for field application. Furthermore, it can be combined with other materials, such as paper and cotton. Generally, like lab on a chip (LOC),4,5 lab-on-a-tip (LOT) can be presented as a sensing platform where one or several tools integrated on a miniaturized single tip,6 and detection can be done by electrical, optical, or mechanical techniques. However, LOT is in infancy and typically developed for a single analyte, but its potential to be developed for multiple analytes is promising that can be integrated with imaging, diagnostics, and therapeutic function.