Correlation Between Blood Lead Level (BLL) and Osteoporosis in Postmenopausal Women in Surabaya Indonesia

Abstract

Lead (Pb) compounds indicate that some toxic effects influence our health such of osteoporosis. This research was to identify source of lead contamination and to analyze the association between blood lead level (BLL), symptom of osteoporosis and occurence of osteoporosis among post menopause women. A cross sectional study was conducted in Surabaya City Indonesia. The sample size was 60 persons, randomly selected from post menopause women age 50-65 years. The observed variables were lead blood level, assessed using atomic absorption spectrophotometry (AAS) and bone mineral density of spine and hip, assessed using Dual X-Ray Examination Absorbtiometry (DXA). The mean value of blood lead level was 11.135 µ/dL. Multiple regression showed that, there was significant correlation between the history of work and Blood lead level (p=0.037). There are significant association between fracture (p=0.027), bone fragility (p=0.008), spinal pain (p=0.016) with osteoporosis. Age (p=0.002), blood lead levell (p=0,055), calcium consumption (p=0.022) and exercise regularly (p=0.08) were together significant correlation with the occurence of osteoporosis. These variables increase the risk of osteoporosis, simultaneously. It implies that to prevent osteoporosis, the possible source of lead contamination should be avoided, meanwhile post menopause women shall improve calcium intake and doing exercise regularly.