| dc.contributor.author | Putri Arasita Rachmawati | |
| dc.date.accessioned | 2013-12-03T04:37:38Z | |
| dc.date.available | 2013-12-03T04:37:38Z | |
| dc.date.issued | 2013-12-03 | |
| dc.identifier.nim | NIM082210101046 | |
| dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/2852 | |
| dc.description.abstract | 1- (3-nitrobenzoyloxymethyl)-5-fluorouracil as a derivative of 5-fluorouracil
has been synthesized in a two step reaction. Subtitution of N1 of 5-fluorouracil with
formaldehyde and followed by esterification reaction with 3-nitrobenzoylchlorida.
Synthesis condition in term of time of reflux in the second step reaction has been
optimized to produce the highest percent product. The product was purified used
(Coloumb Chromatography) CC to obtain three groups of fraction. Based on the
FTIR and 1H-NMR result, 1- (3-nitrobenzoyloxymethyl)-5-fluorouracil is expected to
be present in the third group (fractionation 14-19). | en_US |
| dc.relation.ispartofseries | 082210101046; | |
| dc.subject | 5-Fluorouracil synthesis anticancer esterification | en_US |
| dc.title | SINTESIS 1-(3-NITROBENZOILOKSIMETIL)-5-FLUOROURASIL SEBAGAI UPAYA PENGEMBANGAN OBAT ANTIKANKER | en_US |
| dc.type | Other | en_US |
