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Optimization of Hydroxy Propyl Methyl Cellulose and Carbomer in Diltiazem Hydrochloride Mucoadhesive Buccal Film
(Indonesian Journal of Pharmacy, 2021-02-13)
Diltiazem hydrochloride (HCl) is a drug with low bioavailability due to
the high rate of the first-pass metabolism and a short half-life of the drug
(3-5h); hence, mucoadhesive buccal films were made to overcome ...