Browsing LSP-Jurnal Ilmiah Dosen by Subject "painful diabetic neuropathy"
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The Activity of Red Ginger Oil in Antioxidant Study In Vitro and Antihyperalgesia Effect in Alloxaninduced Painful Diabetic Neuropathy in Mice
(Thai Journal of Pharmaceutical Sciences. 2019, 43 (2): 69-75, 2019-02-28)Background: Red ginger oil (RGO) contains the highest bioconstituent, especially its essential oil which is important for antioxidant, than the other varieties. Chronic diabetic triggers the increase of reactive oxygen ... -
The Binding Prediction of 6-Paradol and its Derivatives on TRPV1 Agonist as a New Compound for Treating Painful Diabetic Neuropathy
(Jurnal ILMU DASAR, Vol. 21 No. 2, Juli 2020 : 133-138, 2020-07-01)Ginger was reported to have a suppressive effect on pain in patients with Painful Diabetic Neuropathy (PDN). Our latest study revealed that 6-shogaol, one of the ginger components, had the best affinity in the Transient ... -
The Improvement of Pain Behavior and Sciatic Nerves Morphology in Mice Model of Painful Diabetic Neuropathy upon Administration of Ginger (Zingiber officinale Roscoe.) Extract and Its Pungent Compound, 6‑Shogaol
(Journal of Natural Science, Biology and Medicine, Volume 10 ¦ Issue 2 ¦ July-December 2019, 2019-07-18)Background: 6-Shogaol is one of the bioactive compounds from ginger (Zingiber officinale Roscoe.) that had been widely used in many diseases. This research was aim to investigate the effect of ginger extract and its pungent ... -
Molecular Docking Analysis of Ginger Active Compound on Transient Receptor Potential Cation Channel Subfamily V Member 1 (TRPV1)
(2019-07-25)Ginger had been reported to ameliorate Painful Diabetic Neuropathy (PDN) in an animal model. Gingerol and shogaol were active compounds of ginger that potentially act on transient receptor potential cation channel ... -
Optimization of Mice Model of Painful Diabetic Neuropathy (PDN)
(2019-07-25)Painful diabetic neuropathy (PDN) is a complication of long-term diabetes mellitus (DM) characterized by hyperalgesia and allodynia. In streptozotocin (STZ)-induced diabetic mice, higher dose of STZ and lengthened ...