Please use this identifier to cite or link to this item: https://repository.unej.ac.id/xmlui/handle/123456789/79096
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dc.contributor.authorBudirahardjo, R
dc.contributor.authorDewanti, I.D.A.R
dc.contributor.authorLestari, P.E
dc.date.accessioned2017-01-23T07:51:22Z
dc.date.available2017-01-23T07:51:22Z
dc.date.issued2017-01-23
dc.identifier.urihttp://repository.unej.ac.id/handle/123456789/79096
dc.descriptionFakultas Kedokteran Gigi Universitas Jember Jl. Kalimantan 37 Jemberen_US
dc.description.abstractCurrently immunomodulator being a topic of conversation in the world of health is used as a prevention or treatment of various diseases. Kpi seeds suspected potentially be imunomdulator. The immune response of dental caries as fagositosisIL-1β, IL-1α and TNF-α. Aim. analyzing modulation of the immune response robusta coffee beans against dental caries. Method. Method. Using experimental animals, which are divided into 5 groups (each with 4 tails). KO: untreated group, KP1; the group made a hole in the tooth + by Kaping CaOH2. KP2: group made a hole in the tooth + by Kaping coffee bean paste fillings 25% + while. KP3: group made a hole in the tooth + by Kaping coffee bean paste fillings 50% + while KP4: group made a hole in the tooth + by Kaping coffee bean paste fillings 75% + while. Week 1, 2, week 3 mice were sacrificed to make the preparation of the teeth and surrounding tissues were for analysis of inflammatory cells, the cell number odontoblasts, the number of se osteoclasts, the sheer number of osteoblasts, the number of fibroblasts with painting HE, the expression of TNF-α, IL-1, by immunohistochemistry. Results. Day 7, 14, dominated the group of inflammatory cells pasta coffee and Ca (OH) 2 numbers looked down but did not differ. SCARA significant number of osteoblasts. Day 21 was dominated by fibroblasts, where coffee and Ca (OH) 2 is no different. Result. Robusta coffee bean and Ca (OH) 2 is equally as having the ability to reduce inflammation, expression of TNF-alpha and IL-1 beta, osteoclasts and improving odontoblasts and osteoblasts. Conclusion. Robusta coffee beans can be used as an alternative material pulp cappingen_US
dc.description.sponsorshipHibah Bersaing 2016en_US
dc.language.isoiden_US
dc.relation.ispartofseriesHibah Bersaing;2016
dc.subjectcoffeeen_US
dc.subjectcariesen_US
dc.subjectS. mutansen_US
dc.subjectthe immune responseen_US
dc.subjectImmunomodulatoryen_US
dc.titlePOTENSI IMUNOMODULATOR BIJI KOPI ROBUSTA TERHADAP KARIES GIGIen_US
dc.typeOtheren_US
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