Aktivitas Fibrinolitik Isolat Bakteri dari Perairan Pantai Papuma Kabupaten Jember Fibrinolytic Activity of Bacterial Isolates from The Papuma Beach on Jember District

Abstract

Papuma Beach has a high bacterial diversity. The results of the previous research were obtained 23 bacterial isolates. A potential that can be exploited was the ability to produce a fibrinolytic enzyme that can be used to solve various problems of thrombosis (myocardial infarction). The purpose of this research was to examine proteolytic and fibrinolytic activities of bacterial isolates from Papuma beach. Proteolytic activity test performed using skim milk agar (SMA) media on 23 bacteria isolate and fibrinolytic activity test using Fibrin Plate Assay method on isolate that are known to have proteolytic activity. Eleven bacterial isolates have proteolytic activity and three bacterial isolates have fibrinolytic activity. Bacterial isolates WU 021012* has the highest proteolytic index i.e. 4.3. Bacterial isolates that has fibrinolytic activity i.e WU 021012*, WU 021001* and WU 021055* with fibrinolytic index 7.01, 6.95, and 5.86 ,respectively.