Effect of Lemuru Fish Oil on Tooth Structure Following Lipopolysaccharide induced Periodontal Infection During Odontogenesis in Rat

Abstract

The aim of the study was to analyze effect of lemuru fish oil on tooth formation especially tooth structure that occurred periodontal infection during odontogenesis. Thirty Wistar rat, male, 5 days age, were divided 3 groups. The first group as control did not do anything. The second group rats were injected LPS to trigger periodontal inflammation. The third group rats were injected LPS and administered lemuru fish oil orally/day/1 ml/300-350g body weight. The rats were decapitated on age of 13 and 21 days. Analyze of tooth structure used HHI index. The result of study was known that inflammation of periodontal during odontogenesis product tooth hypoplasia and hypocalcification. Scoring of HHI index was 9 and 8, mean that hypoplasia and hypocalsification involved all of tooth surface. Lemuru fish oil able suppresses tooth hypoplasia and hypocalcification. Rats that were inducted LPS and treated lemuru fish oil have HHI index aproximally 5 and 6, mean that tooth hypoplasia and hypocalsification involved one of surface of tooth. In addition there were more rats without hypoplasia or hypocalcification. The conclusions were lemuru fish oil proficient to prevent occurred tooth hypoplasia and hypocalsification.