Please use this identifier to cite or link to this item: https://repository.unej.ac.id/xmlui/handle/123456789/58328
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dc.contributor.authorIndah Purnama Sary-
dc.date.accessioned2014-07-14T06:20:12Z-
dc.date.available2014-07-14T06:20:12Z-
dc.date.issued2014-07-14-
dc.identifier.urihttp://repository.unej.ac.id/handle/123456789/58328-
dc.description.abstractAnti-inflammatory activities of naphthyl propionic acid and its derivatives had been studied by molecular mechanics using ChemOffice® 2004 software. Results showed that anti-inflammatory activity of these compounds seem to be determined by a presence of sinister stereochemical configuration of the asymmetric centre of carbon 2 of substituted propionic acid, a presence of an acidic functional group at the carbon 2’ of naphthyl ring, a presence of a heteroatomic substituent having negative inductive effect at the carbon 6’ of naphthyl ring, and interatomic distance between heteroatom-bound H atom and naphthyl ring of 3.128 ± 0.575 Å with the optimum distance of 3.264 Å for naproxen.en_US
dc.language.isootheren_US
dc.subjectstudy on structure, naphthyl propionic aciden_US
dc.titleKAJIAN STRUKTUR SENYAWA TURUNAN ASAM NAFTIL PROPIONAT SEBAGAI KANDIDAT OBAT ANTIRADANG BUKAN STEROIDen_US
dc.typeArticleen_US
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