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DC Field | Value | Language |
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dc.contributor.author | M u h am m ad T au f iq S h id q i | - |
dc.date.accessioned | 2014-01-29T00:03:14Z | - |
dc.date.available | 2014-01-29T00:03:14Z | - |
dc.date.issued | 2014-01-29 | - |
dc.identifier.nim | NIM082010101073 | - |
dc.identifier.uri | http://repository.unej.ac.id/handle/123456789/26802 | - |
dc.description.abstract | K a n ke r pa y ud a r a m e r upa ka n ke ga n a s a n y a n g m e ny e r a n g h a m p i r s e p e r t i g a da r i s e l ur u h ke ga n a s a n y a n g d ij u m pa i pa da wa ni t a . K a n ke r pa y uda r a m e n e m pa t i i ns i de n t e r t i n gg i d a r i s e l ur uh j e ni s ke g a n a s a n s e r t a pe ny e b a b ke m a t i a n ke du a s e t e l a h ka n ke r pa r u pa da wa ni t a . (K a m a r li s , 2009 ; K u m a r e t al , 2007) . B e b e r a pa upa y a pe n go b a t a n p a da ka n k e r m a s i h m e mi li k i k e l e m a ha n , s e hi ngga h a l t e r s e b ut m e n do r o n g pa r a pe n e l i t i u n t uk m e n c a r i a ge n ke m o pr e v e n t i f y a n g b e r a s a l da r i a l a m s e b a ga i s a l a h s a t u ka n d i da t y a n g b e r k ha s i a t a n t i ka n ke r de n ga n e f e k to ks i s i t a s s i s t e m i k y a n g r e n da h un t uk m e mi n im a li s i r t e r j a d i n y a ke ga g a l a n t e r a pi . S a l a h s a t u t a n a m a n y a n g be r pot e n s i s e b a ga i a ge n k e m o pr e ve n t i f k a n ke r a da l a h t a n a m a n ke de l a i ( Gly c ine max L . ) . Da l a m ke de la i t e r da pa t b e b e r a pa ko m po n e n y a n g d i pe r c a y a m e m pu ny a i s i f a t a n t i ka n ke r . S e ny a w a t e r s e b ut a n t a r a l a i n : i nh i b i t o r pr ot e a s e , ph i t a t , s a p o ni n , phi t o s t e r o l , a s a m l e m a k o m e g a 3 da n i s o f l a v o n . D i a n t a r a a n t i k a n ke r t e r s e b ut , pe r h a t i a n t e r b e s a r d i t u j uka n ke pa d a i s o f l a v o n ( K o s wa r a , 2006) . J e ni s s e ny a wa i s o f l a v o n i n i a da l a h ge ni s t e i n , d i a d z e i n, da n g li c i t e i n . B e r da s a r ka n h a l t e r s e b ut , ke d e l a i b e r po t e n s i s e b a ga i a ge n ke m o pr e v e n t i f b a r u t e r m a s uk u n t uk ka n ke r pa y u da r a , m a ka d il a kuk a n pe n e li t i a n l e bi h l a nj ut u n t uk m e n ge t a h u i pe n ga r u h s a r i ke de la i t e r h a da p j u ml a h a po p to s i s s e l pa da ka n ke r pa y uda r a t i ku s W i s t a r put i h ( r att us n or v e gicus ) y a n g d ii nduks i 7, 12 d i m e t i l be n z ( a ) a n t r a s e n ( DM B A ) . J e ni s pe n e li t i a n i n i a d a l a h tr ue e x pe r im e ntal lab or ator ies ( P r a t i k ny a , 2003 ) de n ga n d e s a i n P os t T e s t Only C ont r ol Gr oup De s i gn . P e m il i ha n s u bj e k pe n e li t i a n un t uk pe n ge l o m po ka n da n pe m be r i a n pe r l a kua n de n ga n m e n ggu n a ka n R A L ( R a n c a n ga n A c a k L e n gk a p) ( Noto a t m o dj o , 2002) de n ga n 2 ke l o m po k ko n tr o l , y a i t u ko n t r o l ne ga t i f ( pur da n a qua de s t ) da n ko n t r o l po s i t i f ( DM B A ) s e r t a 3 S e t i a p k e l o m po k pe r l a kua n d il a kuk a n pe m e r i ks a a n hi s t o pa to l o g i m e n ggu n a ka n pe w a r n a a n i m u n o hi s t o ki mi a de n ga n m e t o de T UN E L pa da mi kr o s ko p c a h a y a de n ga n pe m be s a r a n 400 ka l i . H a s il da r i p e m e r i k s a a n d i da pa t ka n r e r a t a j u ml a h A po pto s i s s e l pa da k a n ke r pa y uda r a t i kus m a s i ng m a s i n g ke l o m po k a da l a h K ( ) = 24, K (+ ) = 15, 6 , P 1 = 18, 6, P 2 = 27 , 4, P = 46 , 80. B e r da s a r ka n pe n e li t i a n i ni s a r i ke de l a i ( Gly c ine max L . ) t e r b ukt i da pa t m e ni ngka t ka n a po p to s i s s e l pa d a ka n ke r pa y ud a r a pa da t i kus w i s t a r ( R att us nor v e gicus ) y a ng d ii nduks i DM B A da n d i da pa t ka n do s i s o pt i m a l s a r i ke de l a i t e r h a da p a po p to s i s s e l pa da ka n ke r pa y uda r a s e b e s a r 20 m g/ h a r i . | en_US |
dc.language.iso | other | en_US |
dc.relation.ispartofseries | 0820101010 73; | - |
dc.subject | S ar i K e d e l ai ( Gly c in e m ax. L ) T e r h ad ap Ju m l ah Apop t os is S e l P ad a K an k e r P ayu d ar a T i k u s Wis t a r ( R att u s n or v e gicus ) Yang Diin d u k s i 7, 12 Dim e t il b e n z ( a) an t r a s e n ( DM B A ) | en_US |
dc.title | P E NGAR UH S AR I K E DE L AI ( Gly c in e m ax L. ) T E R HADA P JU M L AH AP OP T OS I S S E L P AD A K AN K E R P AY UD AR A T I K US WI S T AR ( R att u s n or v e gicus ) YA NG DI I ND UK S I 7, 12 Dim e t il b e n z ( a ) an t r a s e n ( DM B A) | en_US |
dc.type | Other | en_US |
Appears in Collections: | UT-Faculty of Medical |
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gdlhub- (10)a_1.pdf | 1.01 MB | Adobe PDF | View/Open |
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