STUDY OF PURINE DEGRADATION IN AQUEOUS SOLUTION BY LACTOBACILLUS FERMENTUM

Abstract

In this study the degradation of extracellular purines by the bacterium Lactobacillus fermentum was examined with aqueous purine solutions. Lactobacillus fermentum was able to decompose free the main control of purine decomposition. In the cases of adenine, guanine, xanthine and hypoxanthine further control was exerted by induction. Furthermore, the uptake of the purines caused differences in the duration and temporal development of the substrate degradation. It was also responsible for the inhibitory effects of the purines on the decomposition of one another when the substrates were used in mixtures. Also, fermentation parameters like biomass and purine concentration, pH, and temperature influenced the purine usage of Lactobacillus fermentum.