Uji Ekstrak Daun Biduri (Calotropis gigantea) Sebagai Denture Cleanser Pada Perendaman Plat Akrilik Heat Cured Terhadap Pertumbuhan Candida albicans

Abstract

The high number of cases of tooth loss in Indonesia has led to the emergence of dentures. Dentures not appropriately kept clean can trigger cases of denture stomatitis due to Candida albicans. Candida albicans is an opportunistic pathogenic fungus found in the oral mucosa. It is often detected on denture plates and causes denture stomatitis. Cleaning the dentures can prevent denture stomatitis. Denture cleaning methods can be done mechanically and chemically. Chemical cleaning often uses synthetic materials such as alkaline peroxide. However, alkaline peroxide can cause side effects in the form of increased porosity on the surface of the acrylic plate, so an alternative natural material, namely biduri leaves (Calotropis gigantea), is needed. This research aimed to determine the inhibitory power of biduri leaf extract and its greatest concentration in inhibiting the growth of Candida albicans. Biduri leaves were extracted using the maceration method and 70% ethanol solvent to produce varying concentrations of 20%, 30%, 40%, and 50%. The growth of Candida albicans was observed and counted using the colony counting method. This research shows an inhibitory power of biduri leaf extract in concentrations of 20%, 30%, 40%, and 50% on the growth of Candida albicans, with a concentration of 50%, which has the most significant inhibitory power.