Browsing LSP-Jurnal Ilmiah Dosen by Author "Verstege, Marleen I."
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Innate stimulatory capacity of high molecular weight transition metals Au (gold) and Hg (mercury)
Rachmawati, Dessy; Alsalem, Inas W.A; Bontkes, Hetty J.; Verstege, Marleen I.; Gibbs, Sue; Blomberg, B. Mary E. von; Scheper, Rik J.; Hoogstraten, Ingrid M. W. van (2018-07-24)Nickel, cobalt and palladium ions can induce an innate immune response by triggering Toll-like receptor (TLR)-4 which is present on dendritic cells (DC). Here we studied mechanisms of action for DC immunotoxicity to gold ... -
Transition metal sensing by Toll-like receptor-4: next to nickel, cobalt and palladium are potent human dendritic cell stimulators
Rachmawati, Dessy; Bontkes, Hetty J.; Verstege, Marleen I.; Muris, Joris; Blomberg, B. Mary E. von; Scheper, Rik J.; Hoogstraten, Ingrid M. W. van (2018-07-24)Background. Nickel was recently identified as a potent activator of dendritic cells through ligating with human Toll-like receptor (TLR)-4. Contact Dermatitis Objectives. Here, we studied an extended panel of transition ...